{"product_id":"karolus-paracetamol-tramadol-tabletas-325mg-37-5mg-con-20","title":"Karolus (Paracetamol\/Tramadol) Tablets 325Mg\/37.5Mg With 20","description":"\u003ch2\u003eCategory\u003c\/h2\u003e\n\u003cp\u003eAnalgesics and antipyretics\u003c\/p\u003e\n\n\u003ch2\u003eLine\u003c\/h2\u003e\n\u003cp\u003eKarolus\u003c\/p\u003e\n\n\u003ch2\u003eBrand\u003c\/h2\u003e\n\u003cp\u003eWeser Pharma\u003c\/p\u003e\n\n\u003ch2\u003eMolecule\u003c\/h2\u003e\n\u003cp\u003eParacetamol\/Tramadol\u003c\/p\u003e\n\n\u003ch2\u003ePresentation\u003c\/h2\u003e\n\u003cp\u003e325 mg\/37.5 mg tablets, box with 20 tablets\u003c\/p\u003e\n\n\u003ch2\u003eLaboratory\u003c\/h2\u003e\n\u003cp\u003eWeser Pharma\u003c\/p\u003e\n\n\u003ch2\u003eIndications\u003c\/h2\u003e\n\u003cp\u003eKarolus is indicated for the treatment of moderate to severe pain. This medication combines the analgesic action of paracetamol with the central analgesic action of tramadol, making it an effective option for the management of postoperative pain, oncological pain, and other types of chronic pain that do not respond adequately to conventional analgesics. Tramadol acts on opioid receptors in the central nervous system, while paracetamol acts primarily at the peripheral level. This combination allows for more complete and effective pain relief.\u003c\/p\u003e\n\n\u003ch2\u003eComposition\u003c\/h2\u003e\n\u003cp\u003eEach Karolus tablet contains: 325 mg of paracetamol and 37.5 mg of tramadol.\u003c\/p\u003e\n\n\u003ch2\u003eContraindications\u003c\/h2\u003e\n\u003cp\u003eKarolus should not be used in patients with known hypersensitivity to any of the components of the formula, in those with severe respiratory depression, acute intoxication by alcohol, hypnotics or opioid analgesics, as well as in patients with uncontrolled epilepsy. This medication is contraindicated in patients with severe liver disease and in those who are receiving monoamine oxidase inhibitors (MAOIs).\u003c\/p\u003e\n\n\u003ch2\u003ePrecautions\u003c\/h2\u003e\n\u003cp\u003eCaution should be exercised when administering Karolus to patients with a history of seizures, respiratory disorders, or those who consume excessive alcohol. It is important to monitor patients at risk of medication abuse, as well as those with a history of opioid dependence. It is recommended to evaluate liver function before starting treatment.\u003c\/p\u003e\n\n\u003ch2\u003eStorage\u003c\/h2\u003e\n\u003cp\u003eStore in a cool, dry place, protected from light and out of reach of children. Do not use after the expiration date indicated on the package.\u003c\/p\u003e\n\n\u003cp\u003ePrescription required.\u003c\/p\u003e\n\u003cp\u003eConsult your doctor.\u003c\/p\u003e","brand":"Weser Pharma","offers":[{"title":"Default Title","offer_id":46299791425761,"sku":"7501300450272","price":503.65,"currency_code":"MXN","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0722\/1500\/3361\/files\/7501300450272.jpg?v=1744714723","url":"https:\/\/wecarepharma.mx\/en\/products\/karolus-paracetamol-tramadol-tabletas-325mg-37-5mg-con-20","provider":"WeCare Pharma","version":"1.0","type":"link"}